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hosted by: Dr. Teri Fisher
Episode 9: What are Exosomes?

Episode 9: What are Exosomes?

The Aesthetic Uses of Stem-Cell Derived Exosomes

In this podcast episode, Dr. Teri Fisher discusses exosomes and their role in dermatologic anesthetic treatments. Exosomes are nano-sized extracellular vesicles released by most cell types, which contain proteins used for communication between cells. These vesicles can be derived from various stem cells and are not living organisms themselves, making them cleanable, purifiable, and concentratable for medical purposes. This provides exciting possibilities for using exosomes in a clinical setting.

For more information or to book an appointment with Dr. Fisher, feel free to book your consultation online or phone 604-261-9121.

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Today’s Guest

Dr. Teri Fisher

Dr. Teri Fisher is a physician who combines his meticulous and scientific approach with his artistic eye and skilled dexterity to provide outstanding results for his patients. He is known for connecting with his patients to understand their needs and leaving them feeling healthy, confident, and empowered with improved “Health Esteem.” Dr. Fisher has BSc, BEd, MSc, MD, CCFP (SEM) degrees and is a specialist in Aesthetic Medicine, Sport & Exercise Medicine. He is also a clinical assistant professor at the University of British Columbia and host of the “Anti-Aging Insights Podcast”. He is also a member of the Canadian Association of Sports & Exercise Medicine, Canadian College of Family Physicians, and Canadian Medical Association.

Key take aways

  • Exosomes are nano-sized extracellular vesicles released by cells to communicate with each other.
  • Exosomes contain proteins and are used to send messages to other cells to help them function in a healthy and efficient manner.
  • Exosomes can be derived from various living organisms and can be purified, harvested, and concentrated for medical use.
  • Exosomes have important roles in disease states and the health of our skin.
  • The ability to store and transport exosomes allows for clinical use in medicine.
  • The clinical uses of exosomes are currently being researched and include the treatment of various skin conditions and diseases.


Episode Transcript

Dr. Teri Fisher:  Hello, and welcome to this week’s episode of the podcast. It’s great to have you along as always. Thank you to all of you that have been giving us some fantastic feedback on the podcast. It’s really appreciated, and it’s a lot of fun bringing these to you.

Today, we’re talking about a topic that is very, very hot right now in social media. It is a very topical issue right now when it comes to dermatologic anesthetic treatments, and that is the whole topic of exosomes. You may have seen these on social media. People are sharing posts about having treatments with exosomes, but the truth is I don’t think that there’s a very good understanding about what these actually are and how these work. So today we’re going to tackle this. We’re going to talk about what exosomes are. We’re going to talk about how they’re created, and of course what they do. How do they function? How can they help when it comes to medicine and your skin, dermatological procedures, treatments, and aesthetic medicine treatments as well?

Exosomes are nano-sized extracellular vesicles released by various cell types. They act as small containers carrying proteins and other biological materials to facilitate communication between cells. These vesicles can be considered as microscopic “delivery guys” that transport important proteins from one cell to another. Exosomes are outside the cells, meaning they have been released and can move to different locations. They are extremely small, ranging from 30 to 200 nanometers, smaller than the cells themselves.

The ability to isolate, purify, and concentrate exosomes makes them valuable for medical purposes. They can be obtained from different living organisms, such as animals or plant cells. While exosomes are derived from living cells, they are not living organisms themselves. This characteristic allows exosomes to be manipulated, stored, and transported for clinical use.

Exosomes have diverse clinical applications. In the field of dermatology and aesthetics, they show promise in treating various conditions. Here are some specific examples:

  1. Eczema (Atopic Dermatitis): Exosomes can decrease the immune response and inflammation associated with eczema. They also improve the skin barrier function, providing relief from redness, itching, and flaking.

  2. Scarring: Exosomes promote the migration and proliferation of cells involved in tissue repair, such as fibroblasts. They facilitate collagen deposition and wound healing, leading to reduced scarring. When used in conjunction with treatments like CO2 lasers, exosomes can enhance recovery and minimize side effects.

  3. Hair Loss: Early studies suggest that exosomes stimulate hair follicle proliferation and accelerate the growth phase (anagen) of hair. They may have a role in improving hair thickness and addressing hair loss when used in combination with other treatments like microneedling or PRP (Platelet-Rich Plasma).

  4. Pigmentation Disorders: Exosomes have shown potential in treating hyperpigmentation disorders like melasma. They contain proteins that affect the function of keratinocytes and melanocytes, the cells responsible for skin coloration. Exosomes may help regulate and improve irregular pigmentation.

  5. Skin Aging: Exosomes may contribute to collagen synthesis, promoting more youthful and elastic skin. They also show potential in reducing damage caused by UV exposure, a major factor in skin aging.

It’s important to note that while these findings are promising, further research is still needed to fully understand and validate the efficacy of exosomes in these applications. However, their potential benefits make them an exciting area of study and development in the field of aesthetic medicine.

If you’re interested in learning more about exosomes or exploring treatments incorporating exosomes, it’s recommended to contact a reputable clinic or medical professional experienced in this area.

Thank you once again for tuning into the podcast. I hope this was fun for you. I hope it was nice to be able to learn a little bit more about exosomes. As always, feel free to reach out to me. I’m only too happy to have a chat with you, about anything that you’ve heard about on the podcast. On Instagram I am Dr. Teri Fisher, D R T E R I F I S H E R. Feel free to reach out to me at Anti-Aging Vancouver as well, at or on my personal website at DrTeriFisher.Com. Until next time, be well, and talk to you soon.

Next Episode
Episode 10: Health Esteem and Aesthetic Medicine

About the Show

Anti-Aging Insights Podcast

Join renowned Anti-Aging, Aesthetic, and Sport & Exercise physician, Dr. Teri Fisher, as he explores the latest news, treatments, technologies, research and developments in non-surgical cosmetic and anti-aging medicine. Throughout each episode, Dr. Fisher is your guide to help you understand what you can do to look and feel amazing, and to improve the quality of your life today and tomorrow. He breaks down the medical evidence to determine what works (and what doesn’t) to help you better understand the world of aesthetic medicine. Dr. Fisher interviews experts and leading practitioners in the field to discuss the latest strategies and techniques for maintaining health and wellness as we age. Whether you’re looking to improve your physical appearance or overall well-being, this podcast has something for anyone who is interested in maintaining their health, youth, and vitality as they get older.

Please note: This podcast is for informational purposes only and is not intended to be a substitute for professional medical advice. Always seek the advice of your qualified healthcare provider before starting any treatment.

Visit Dr. Teri Fisher’s website here.

Dr. Teri Fisher

Dr. Teri Fisher is an Aesthetic and Sport Medicine Physician, and a Clinical Assistant Professor at the University of British Columbia. He has been a podcast host for over 10 years and is particularly known for his approachable, thoughtful, and friendly manner. It is through his aesthetic medicine practise that Dr. Fisher combines his passions for art, science, and technology. For more information about Dr Fisher, please click here.

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