Wrinkle Reduction with Neuromodulators

vancouver botox injections

Wrinkle Reduction with Neuromodulators

Are you considering neuromodulators in Vancouver, BC? First, learn about this most popular treatment for facial wrinkles. It is a quick, effective, non-surgical treatment most often used to reduce the appearance of forehead wrinkles, crow’s feet, and frown lines (glabellar lines) visible between the eyebrows.

Neuromodulators may also be used to minimize: chin dimpling, bunny scrunch lines on the top/sides of the nose, smoker’s lines, and sagging brow.

For more information about neuromodulator injections and costs, contact Anti-Aging Medical & Laser Clinic.

What are neuromodulators?

Neuromodulators are an injectable prescription medication (onabotulinumtoxinA) that temporarily relaxes facial muscles to improve the appearance of dynamic facial wrinkles.  In 2002, they received FDA approval for the treatment of moderate to severe frown lines (glabellar lines).

As we age, a lifetime of repeated facial muscle contractions become etched into our skin. Wrinkles caused by these contractions are known as dynamic wrinkles (sometimes called expressive wrinkles).  Where static wrinkles are noticeable all the time, dynamic wrinkles are a result of repeated muscle movements when we smile, laugh or frown.

Neuromodulators block the signals sent by nerves to muscles – relaxing the muscles to reduce the appearance of dynamic wrinkles. When injected by an experienced doctor, they do not numb the area of injection and patients still have sensation in the area being treated. In 3 to 6 months, as new nerve endings grow and neuromodulators break down, blocked signals from nerves to muscles are restored.

Neuromodulators Safety

Neuromodulators were amongst dermatological procedures studied in a 2011 multi-centre study that assessed the incidence of adverse effects of cosmetic dermatological including laser and dermal fillers, The study findings, published in JAMA (Journal of the American Medical Association) revealed that neuromodulators caused side effects in 1 out of every 3,333 cases. It’s important to note that treatments were administered by doctors who were highly experienced. The small number of side effects reported may have increased if treatments were performed by doctors less experienced with neuromodulators injections.

Benefits of neuromodulators

  • Quick wrinkle treatment with immediate results
  • Injections are relatively painless for most people
  • Non-surgical
  • Safe and effective
  • Long lasting
  • No downtime


Please call us at (604) 261-9121 or fill the form below

    Am I a good candidate?

    If you have visible crow’s feet, frown lines between the eyes, forehead wrinkles, or other dynamic facial wrinkles, you may be a candidate for neuromodulator injections.

    Neuromodulators treatment contraindications:

    Do not have neuromodulator treatments if you allergic to or have sensitivity to Botulinum toxin or any of the components of neuromodulators, infection at the injection site; neurological disorders such as myasthenia gravis, multiple sclerosis, ALS, Lambert Eaton syndrome, muscular dystrophy; if you are pregnant or breastfeeding.

    For more complete information on contraindications, please consult a physician. See neuromodulator prescribing information.

    Before the treatment

    • Avoid red wine for 1 day before the treatment.
    • Avoid Aspirin, Motrin, Advil (ibuprofen), non-steroidal anti-inflammatories (NSAIDs) and other blood thinners for 1 day before the treatment.
    • If you have had any infection or cold sore near the injection site talk to your doctor before treatment. You may be prescribed Valtrex or another anti-viral medication to prevent an outbreak.
    • Though severe or persistent bruising is an infrequent side effect of neuromodulator treatments, it can occur in some patients. Because bruising is difficult to predict, avoid scheduling social events that occur in the two weeks following treatment.

    What happens during the treatment?

    Before a treatment, the doctor will consult with you and decide upon a treatment plan – taking into consideration which areas would most benefit you and the improvement you desire. A numbing cream may be applied and allowed to take effect for a few minutes, and prior to each injection, the injection site may be further numbed with an ice pack. The combination of topical anaesthetic and ice pack freezing make the injections quite tolerable.

    After the treatment

    After your treatment, common injection-related reactions may occur such as swelling, bruising, redness, tenderness, itching, and discolouration at the injection site. Minor injection site bruising, if it does occur, is easily covered.

    • No excessive sun or heat until any initial swelling and redness have resolved.
    • Avoid squeezing or massaging the treated areas for several hours after treatment as this could subtly change the results.
    • Avoid laying your head down for 4 hours after your treatment.
    • No excessive exercise for 24 hours after the treatment.

    Recovery time: No downtime required. Minimal injection site bruising is easily covered and usually resolves in a few days. Patients who experience more noticeable bruising may feel more comfortable taking social downtime until bruising subsides.

    How many treatments will I need?

    In most cases, neuromodulators will last for 3 or 4 months. Patients may want a few treatments per year.

    Once eliminated by the body and its effects have worn off, you’ll look as you did prior to treatment. After prolonged use of neuromodulators, most people need less to achieve similar results.

    Other treatment options

    Our Vancouver, BC, Canada skin and laser clinic offers many wrinkle treatments with similar benefits as neuromodulators. A consultation will determine which treatment is right for you.

    More information about neuromodulators

    More videos about neuromodulators

    Great Experience

    The people here are very friendly and helpful and really know what they’re doing! Will definitely be back!!

    I did [Neuromodulators] and [Deoxycholic Acid] treatments. Very friendly and helpful staff who really seem to care.

    I'm feeling great! I came here because I have friends have come here.

    This testimonial was [edited] to comply with Health Canada requirements.


    Dr. Frame was recommended to me by a friend. Having never had neuromodulators before, I was initially a bit nervous, but really wanted to do something about those lines that seem to keep showing up in the mirror, so I finally called his clinic. I was very impressed by the attentiveness and professionalism of his staff. They welcomed me in, offered me tea, and really made me feel at ease. Dr. Frame’s nurse was very knowledgeable and listened to all of my concerns. I was then introduced to Dr. Frame, who was very reassuring and did not make me feel pressured into having the treatment. He simply listened to my worries and thoroughly explained how the treatment worked and what results I could expect afterwards. I decided to go ahead with the neuromodulator treatment that day. I am supposed to go back in two weeks for a follow-up, but after only one week, I am thrilled with the results. I will definitely go back in 3 or 4 months when the results wear off.

    Charlene M.

    I suffered from migraine headaches for years and Dr. Frame has given my life back to me with the help of [Neuromodulators] injections for migraines. The staff is very caring and understanding especially his wife Nadine. I would not hesitate to recommend [Neuromodulators] treatment by Dr. Frame to any migraine sufferer. It has made a difference in my life.

    This testimonial was [edited] to comply with Health Canada requirements.

    I chose this clinic because I read a review in the Vancouver Sun by another migraine sufferer. I wanted a medical doctor to perform the Botox injections. Dr. Frame is very knowledgeable and truly cares about his patients.

    I would not trust just anybody to perform anything on my face that did not have medical training and knowledge. Dr. Frame and his staff are very caring.


    For those that are either new or familiar with neuromodulators and/or facial fillers, this clinic is outstanding in both service and results. I am an RN and have been in the plastic surgery and medical aesthetics industry since 1998 and it wasn’t until December 2015 at Dr. Frame's office that I finally found the best injector I have EVER had. The team is kind, informative and caring. On my first visit, I was given a full consultation and Nadine developed a care plan for me. She was very clear that it was not their intention of trying to accomplish this in one treatment session, unlike other clinics that I have encountered. She asked me what my budget was and we worked from there.

    When I was ready to have my treatment I saw the assistant come in with multiple syringes all containing different amounts of Botulinum toxin.(I know this may not seem important to most people, however, it makes a difference as the needle on the syringe becomes dull very quickly after multiple injections). Most clinics don’t do this. The filler I received was outstanding, NEVER have I had such a comfortable injection process and the results were beautiful. Facial fillers require a thorough understanding of anatomy but also a creative eye, that coupled with a gentle hand is almost impossible to find but I found it with Dr. Frame. I have posted this from a nursing and consumer perspective because I know what happens in this medical aesthetic industry and how poorly many are trained. I recently moved to Vancouver I did a lot of research on many clinics prior to entering Dr. Frame's clinic and it was well worth it. If you are new to these procedures….please start here at this clinic.

    Paris City Registered Nurse

    I’m very happy with the results I’ve gotten with Dr. Frame. We moved here 6 years ago from Toronto and it took some time to find the right doctor. I tried a few other well known west-side doctors with results that weren’t great. Dr. Frame listens to what I want – a natural look that’s not a face full of neuromodulators. His bedside manner is calming and informative. You just may get a few free anti-aging tips along the way – he’s just that good. Most importantly, we’ve all seen the bad work that’s out there in Vancouver and I feel for those women. Too many neuromodulators and filler. Why can’t they see what we see? Dr. Frame is an artist when it comes to ensuring a natural look. When I look in the mirror I’m thankful to have found someone as skilled as Dr. Frame.

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