Technology
A topical polydeoxyribonucleotide (PDRN) formula applied immediately after microchannel-creating procedures to aid skin recovery and quality.
Anti-Aging Clinic can explain how this technology may fit into care, answer your questions, and help you explore the next step with a specialist.
Book a ConsultationAbout this technology
VAMP is a topical regenerative formula built around PDRN (polydeoxyribonucleotide), a fragment of DNA derived from salmon. It is applied immediately after in-clinic procedures that briefly and deliberately disrupt the skin barrier, such as microneedling, RF microneedling or laser, because the microchannels these create open a short window in which a topical formula may be absorbed more readily than it would through intact skin. It is a step layered onto another treatment rather than a stand-alone device, and in Canada it is used topically only.
PDRN is studied as a 'biological messenger', a molecule proposed to prompt the skin's own repair activity. Laboratory and clinical research (largely on injectable PDRN) suggests it may stimulate fibroblasts, the cells that produce collagen and elastin, and may help calm inflammation, which is the rationale for using it to aid recovery and skin quality. Applied after a microchannel-creating procedure, the formula is intended to reach beneath the surface during the brief period the barrier is open.
It is worth being clear about the evidence: most published PDRN research concerns injected product, and high-quality evidence for topical PDRN specifically is limited and largely mechanism-based. Results vary between individuals and are not guaranteed, and VAMP is best understood as a complement to the procedure it follows rather than a treatment proven on its own.
VAMP is used as an adjunct immediately after barrier-disrupting procedures such as microneedling, RF microneedling and laser resurfacing. It is typically advised as part of a series spaced over several weeks to aid progressive change, with periodic maintenance to help sustain hydration, elasticity and overall skin quality over time. Whether it is appropriate, and how it fits a plan, is decided with your provider based on your skin, goals and the procedure it accompanies.
Anti-Aging Medical & Laser Clinic
Anti-Aging Medical & Laser Clinic can help you explore this technology, related treatments, and connected concerns.
Used after a microchannel procedure, VAMP aims to aid post-procedure recovery, hydration and overall skin quality, complementing the collagen-remodelling goals of the treatment it follows. Because the evidence for topical PDRN is still limited, these are reasonable aims rather than promised outcomes. Results vary, appear gradually, and are best assessed over a series rather than after a single application.
VAMP is generally well tolerated when applied immediately after a procedure. It is not advised for people with a known allergy to fish-derived ingredients (PDRN is sourced from salmon), for anyone with an active infection or open wound in the treatment area, or, as a precaution, during pregnancy or breastfeeding.
Regulatory status (kept separate from efficacy): injectable PDRN products (such as Rejuran, available in some countries) are not currently authorized by Health Canada. At this clinic PDRN is used topically only, applied after treatments that create microchannels, in keeping with Canadian regulations. Health Canada status describes what is permitted, not proof of a particular result.
Related Treatments
Controlled laser energy that renews the skin surface and stimulates repair, helping soften texture, scars, fine lines and sun damage.
Combines fine needles with radiofrequency energy delivered at controlled skin depths to stimulate collagen and help remodel scars and laxity.
An in-clinic regenerative facial that pairs a microchannel-creating procedure with a topical PDRN (salmon-DNA) formula to aid recovery and skin quality.
Conditions It May Help Address
The relationship between a technology and a concern depends on the treatment plan, patient assessment, and how the technology is being used.
Acne is a skin condition that can affect people of all ages and skin types. Our physicians assess what is happening in your skin and help you choose an appropriate medical treatment, maintenance and preventive plan as well as your at-home skincare.
Visible pores and an irregular skin surface often linked to oil, acne, or aging.
Skin that looks less smooth or radiant and feels uneven because of surface irregularity.
Visible facial creases that develop from repeated expression, collagen loss, sun exposure and skin dryness.
Reduced firmness and mild tissue descent related to aging and the decline of collagen and elastin.
Loose neck skin, horizontal creases, or visible muscle bands that can reduce definition of the neck and jawline.
Changes in skin colour or texture from rapid stretching, injury, or surgical healing.
Talk with Anti-Aging Clinic about your goals and the options that may be worth exploring.
FAQ
PDRN (polydeoxyribonucleotide) is a fragment of DNA used because its structure is highly similar to human DNA, which is thought to let skin cells recognise it. It is studied as a signal that may aid the skin's natural repair processes, including fibroblast and collagen activity and a calming of inflammation. Salmon is a common, well-characterised source of these DNA fragments. The mechanism is promising, but evidence for topical use is still limited, so it is used to aid, not replace, the procedure it accompanies.
No. Health Canada does not currently authorize the injectable use of PDRN-based products. At our clinic PDRN is used topically only, applied immediately after treatments that create microchannels in the skin, which complies with Canadian regulations while still allowing the formula to be absorbed after the procedure.
VAMP is usually advised as part of a series spaced over several weeks, with occasional maintenance afterward. The right number is individual and depends on your skin, your goals and the procedure it accompanies, so your provider will outline a plan at consultation, with realistic expectations and no guarantees.
It is not advised if you have a known allergy to fish-derived ingredients, an active infection or open wound in the treatment area, or if you are pregnant or breastfeeding (as a precaution). Let your provider know your history so suitability can be confirmed.
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Anti-Aging Medical & Laser Clinic combines medical assessment, individualized planning, physician oversight, and a broad range of treatment options in its Vancouver clinic.
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